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Antibiotics : actions, origins, resistance by Christopher Walsh.

Por: Walsh, Christopher.
Tipo de material: materialTypeLabelLibroEditor: Washington, D.C. : ASM Press, c2003Descripción: x, 335 p. : il. (algunas col.) ; 26 cm.ISBN: 1555812546.Tema(s): Antibióticos | Resistencia microbiana de los medicamentos | FarmacologíaClasificación CDD: 615.329
Contenidos:
Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
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Libros Biblioteca Laura Manzo - Universidad Nacional de Quilmes
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Libros Biblioteca Laura Manzo - Universidad Nacional de Quilmes
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Libros Biblioteca Laura Manzo - Universidad Nacional de Quilmes
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Libros Biblioteca Laura Manzo - Universidad Nacional de Quilmes
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Libros Biblioteca Laura Manzo - Universidad Nacional de Quilmes
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Incluye referencias bibliográficas (p. 297-328) e índice.

Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.

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