Antibiotics : actions, origins, resistance
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| Format: | Book |
| Language: | English |
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Washington, D.C. :
ASM Press,
c2003.
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Table of Contents:
- Antibiotics : initial concepts
- Introduction to major antibiotic classes and modes of action
- Antibiotics that act on cell wall biosynthesis
- Antibiotics that block bacterial protein biosynthesis
- Antibiotics that block DNA replication and repair : the Quinolones
- Other targets of antibacterial drugs
- Natural and producer immunity versus acquired resistance
- Enzymatic destruction or modification of the antibiotic by resistant bacteria
- Antibiotic resistance by efflux pumps
- Antibiotic resistance by replacement or modification of the antibiotic target
- Regulation of antibiotic biosynthesis in producer organisms
- Polyketide antibiotic biosynthesis : assembly line enzymology
- Enzymatic assembly lines for nonribosomal peptide antibiotics
- Biosynthesis of other classes of antibiotics
- New looks at targets
- New molecules
- Contexts and challenges for the use of new antibiotics.